He had his beginnings with "BFAM741", a co-release with Julian Jordan another artist signed to Spinnin' Records label in "BFAM". In 2012, he won the Nightlife Award during SLAM! FM DJ Talent of the Year Award. Also in 2012, his remix of "Your Body" appeared as "Your Body (Martin Garrix Remix)" on Christina Aguilera's Deluxe version of the album Lotus. The song is written by Max Martin, Shellback and Savan Kotecha. His track "Just Some Loops", a collaboration with TV Noise appeared on the compilation album Loop Masters Essential, Volume 2.
In 2013, he co-released "Torrent" with Sidney Samson on Tiësto's Musical Freedom label. Garrix gained considerable fame through his own solo release "Animals" released on June 16, 2013 on Dutch record label Spinnin Records, becoming a hit in a great number of charts in Europe, and quickly became the youngest person ever to reach the #1 spot on Beatport. The track also appears on Hardwell's album Hardwell presents 'Revealed Volume 4'. On September 30th, 2013, Garrix released a remix of "Project T" by Sander Van Doorn, Dimitri Vegas and Like Mike which quickly hit #1 on the beatport charts. Garrix appeared on DJ mag's top 100 DJs list 2013 as a new entry at number 40.